It's one of the nice things about having these properties in our back pocket... If we want to use something we own as a source for a game, it's easy to do. So yeah, you never know. We've got this giant product to launch, but once that's done we'll consider next steps."
Earlier this year in an interview with Game Informer, Mass Effect 3 Executive Producer Casey Hudson told the gaming magazine that, "A lot of people say that they want to see an MMO, I think that kind of makes sense for this universe.
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Source: Industry Gamers